Evolution of the Protein Repertoire
Abstract
Most proteins have been formed by gene duplication, recombination, and divergence. Proteins of known structure can be matched to about 50% of genome sequences, and these data provide a quantitative description and can suggest hypotheses about the origins of these processes.
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We thank M. Madera, E. Koonin, and A. Finkelstein for comments on the manuscript. J.G. has a Burroughs-Welcome Fellowship from the Program in Mathematics and Molecular Biology, and C.V. has a Boehringer Ingelheim Predoctoral Fellowship.
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Volume 300 | Issue 5626
13 June 2003
13 June 2003
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American Association for the Advancement of Science.
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- Cyrus Chothia et al.
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