Terms & Properties

Preferred Name:  Blast Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive

Definition:  An advanced phase of chronic myeloid leukemia. It is characterized by: 1. the presence of blasts in the peripheral blood or bone marrow that are at least 20% of the peripheral blood white cells or of the nucleated cells in the bone marrow respectively, or 2. an extramedullary proliferation of blasts, and/or 3. when there are large aggregates and clusters of blasts in the bone marrow biopsy specimen (adapted from WHO, 2001).

NCI-GLOSS Definition:  A phase of chronic myelogenous leukemia in which 20% or more of the cells in the blood or bone marrow are blast cells (immature blood cells). When tiredness, fever, and an enlarged spleen occur during the blastic phase, it is called blast crisis.

Label:  Blast Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive

NCI Thesaurus Code:  C9110 (Search for linked caDSR metadata)   (search value sets)

NCI Metathesaurus Link:  C0005699  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)

blast crisis

Blast Phase Chronic Granulocytic Leukemia

Blast Phase Chronic Myelocytic Leukemia

Blast Phase Chronic Myelogenous Leukemia

Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive

Blast Phase Chronic Myelogenous Leukemia, BCR::ABL1 Positive

Blast Phase Chronic Myeloid Leukemia

Blast Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive

Blast Phase Chronic Myeloid Leukemia, BCR::ABL1 Positive

Blast Phase CML

Blastic Phase Chronic Granulocytic Leukemia

Blastic Phase Chronic Myelocytic Leukemia

Blastic Phase Chronic Myelogenous Leukemia

blastic phase chronic myelogenous leukemia

Blastic Phase Chronic Myeloid Leukemia

Blastic Phase CML

External Source Codes: 

UMLS CUI

C0005699

Other Properties:

Name	Value (qualifiers indented underneath)
code	C9110
Contributing_Source	Cellosaurus
Legacy Concept Name	Blast_Phase_Chronic_Myelogenous_Leukemia
Neoplastic_Status	Malignant
Semantic_Type	Neoplastic Process

Additional Concept Data: 

Defined Fully by Roles: Yes

URL:https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&ns=ncit&code=C9110