Volume 70, Issue 3 e30193
BRIEF REPORT

Side effects following COVID-19 vaccination in pediatric patients with sickle cell disease

Jennifer A. Belsky

Corresponding Author

Jennifer A. Belsky

Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, USA

Division of Pediatric Hematology Oncology, Riley Hospital for Children, Indianapolis, Indiana, USA

Marian University College of Osteopathic Medicine, Indianapolis, Indiana, USA

Correspondence

Jennifer A. Belsky, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA.

Email: [email protected]

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Whitney R. Carroll

Whitney R. Carroll

Marian University College of Osteopathic Medicine, Indianapolis, Indiana, USA

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Anna Feliciano

Anna Feliciano

Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, USA

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Seethal A. Jacob

Seethal A. Jacob

Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, USA

Division of Pediatric Hematology Oncology, Riley Hospital for Children, Indianapolis, Indiana, USA

Center for Pediatric and Adolescent Comparative Effectiveness Research, Indianapolis, Indiana, USA

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First published: 30 December 2022

Abstract

Vulnerable patient populations have seen decreased rates of vaccination against SARS-CoV2-19 (COVID-19) due to hesitancies and distrust, magnified by a paucity of data for certain populations. The rate of COVID-19 vaccination in children with sickle cell disease (SCD) remains low despite the risk for severe complications, resulting in continued infections and hospitalizations from COVID-19. We sought to describe vaccine reactions, including vaso-occlusive crises, emergency department visits, and hospitalizations, in children with SCD. Our findings will start to provide the necessary vaccine side effect data to inform patients, caregivers, and clinicians considering the COVID-19 primary vaccination series.

CONFLICT OF INTEREST

The authors declare that there is no conflict of interest.

The full text of this article hosted at iucr.org is unavailable due to technical difficulties.