Abstract
A 72-year-old man who was undergoing chronic ambulatory peritoneal dialysis developed peritonitis due to Prototheca wickerhamii. Results of in vitro sensitivity testing revealed that the organism was sensitive to amphotericin B (MIC, 0.4 micrograms/mL) but resistant to fluconazole (MIC, greater than 80 micrograms/mL). The patient was successfully treated medically with a combination of intravenous amphotericin B and oral doxycycline.
MeSH terms
- Administration, Oral
- Aged
- Amphotericin B / pharmacology
- Amphotericin B / therapeutic use
- Doxycycline / administration & dosage
- Doxycycline / therapeutic use
- Drug Resistance, Microbial
- Fluconazole / pharmacology
- Humans
- Infections / drug therapy
- Infections / etiology
- Injections, Intravenous
- Male
- Peritoneal Dialysis, Continuous Ambulatory*
- Peritonitis / drug therapy
- Peritonitis / etiology*
- Prototheca / drug effects
- Prototheca / isolation & purification*
Substances
- Amphotericin B
- Fluconazole
- Doxycycline