Daddy issues: paternal effects on phenotype

Oliver J Rando

doi:10.1016/j.cell.2012.10.020

Daddy issues: paternal effects on phenotype

Cell. 2012 Nov 9;151(4):702-708. doi: 10.1016/j.cell.2012.10.020.

Author

Oliver J Rando¹

Affiliation

¹ Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, USA. Electronic address: oliver.rando@umassmed.edu.

Abstract

The once popular and then heretical idea that ancestral environment can affect the phenotype of future generations is coming back into vogue due to advances in the field of epigenetic inheritance. How paternal environmental conditions influence the phenotype of progeny is now a tractable question, and researchers are exploring potential mechanisms underlying such effects.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Epigenesis, Genetic*
Female
Gene Expression Regulation*
Gene-Environment Interaction*
Humans
Male
Phenotype
Plants / genetics

Abstract

Publication types

MeSH terms

Grants and funding