Lysogenic conversion of staphylococcal lipase is caused by insertion of the bacteriophage L54a genome into the lipase structural gene

J Bacteriol. 1986 May;166(2):385-91. doi: 10.1128/jb.166.2.385-391.1986.

Abstract

Staphylococcus aureus PS54 manifests no lipase (geh) activity. This is due to the insertion of bacteriophage L54a DNA into the geh structural gene. The nucleotide sequence of this 2,968-base-pair DNA fragment was determined. Lipase deduced from the nucleotide sequence is a polypeptide of 690 amino acids which extends from nucleotide 706 to 2776.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Base Sequence
  • Chromosome Deletion
  • DNA Restriction Enzymes / metabolism
  • DNA, Bacterial / analysis
  • DNA, Viral / analysis
  • Genes*
  • Lipase / genetics*
  • Lysogeny*
  • Mutation
  • Staphylococcus / enzymology*
  • Staphylococcus Phages / genetics*

Substances

  • DNA, Bacterial
  • DNA, Viral
  • Lipase
  • DNA Restriction Enzymes

Associated data

  • GENBANK/M12715