SARS-CoV-2-related paediatric inflammatory multisystem syndrome, an epidemiological study, France, 1 March to 17 May 2020

Euro Surveill. 2020 Jun;25(22):2001010. doi: 10.2807/1560-7917.ES.2020.25.22.2001010.

Abstract

End of April 2020, French clinicians observed an increase in cases presenting with paediatric inflammatory multisystem syndrome (PIMS). Nationwide surveillance was set up and demonstrated temporospatial association with the coronavirus disease (COVID-19) epidemic for 156 reported cases as at 17 May: 108 were classified as confirmed (n = 79), probable (n = 16) or possible (n = 13) post-COVID-19 PIMS cases. A continuum of clinical features from Kawasaki-like disease to myocarditis was observed, requiring intensive care in 67% of cases.

Keywords: COVID-19; Kawasaki disease; SARS-CoV2; children; inflammation; myocarditis; post-infectious disease.

MeSH terms

  • Betacoronavirus
  • COVID-19
  • Child
  • Child, Preschool
  • Coronavirus / isolation & purification*
  • Coronavirus Infections / complications
  • Coronavirus Infections / diagnosis*
  • Coronavirus Infections / immunology
  • Disease Outbreaks
  • Female
  • France / epidemiology
  • Humans
  • Male
  • Pandemics
  • Pneumonia, Viral / complications
  • Pneumonia, Viral / diagnosis*
  • Pneumonia, Viral / immunology
  • SARS-CoV-2
  • Systemic Inflammatory Response Syndrome / epidemiology*
  • Systemic Inflammatory Response Syndrome / etiology

Supplementary concepts

  • pediatric multisystem inflammatory disease, COVID-19 related