ABC Heart Fail Cardiomyop 2023; 3(1): e20230017
Post-COVID Cardiomyopathy
Marcio Roberto Moraes de Carvalho 
, Jocemir Ronaldo Lugon , Antonio Jose Lagoeiro Jorge
Myocardial inflammation, COVID-19, and HFpEF
Myocardial inflammation is widely considered to be one of the main factors in the development of heart failure (HF). It is believed that persistent myocardial inflammation plays a central role in the development of adverse left ventricular remodeling after myocardial infarction, as well as in the pathogenesis of dilated cardiomyopathy and heart failure with preserved ejection fraction (HFpEF). –
In May 2020, Tavazzi et al. reported the first case of acute cardiac injury with the finding of SARS-CoV-2 particles and low-grade inflammation in the myocardium, not accompanied by cardiomyocyte necrosis. An important discussion is whether the myocardial changes are caused by direct viral damage to the heart or vasculature or by a cytokine storm related to the infection. It is mainly known that cardiac inflammatory changes induced by viruses are capable of triggering HFpEF and heart failure with reduced ejection fraction. There is currently a growing interest in identifying patients with COVID-19 at risk of developing virus-related HF and cardiovascular problems.
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Keywords: Adult; Cardiomyopathies; Child
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