A thrombosed external hemorrhoid is a complication of external hemorrhoids. Usually, this disease is accompanied by severe pain that lasts for several days. The common conservative treatment is a slow, ineffective pain reliever. Surgery produces a lot of discomfort and inconvenience, affects the patient's quality of life, and presents some risks of post-operative complications. The purpose of this article is to propose an elegant compounded preparation to quickly treat the pain associated with thrombosed external hemorrhoids with a minimum of side effects and complications.