Resolution: 3.96 Å
EM Method: Single-particle
Fitted PDBs: 8d21
Q-score: 0.395
Andrews SF, Cominsky LY, Shimberg GD, Gillespie RA, Gorman J, Raab JE, Brand J, Creanga A, Gajjala SR, Narpala S, Cheung CSF, Harris DR, Zhou T, Gordon I, Holman L, Mendoza F, Houser KV, Chen GL, Mascola JR, Graham BS, Kwong PD, Widge A, Dropulic LK, Ledgerwood JE, Kanekiyo M, McDermott AB
Sci Transl Med (2023) 15 pp. eade4976-eade4976 [ DOI: doi:10.1126/scitranslmed.ade4976 Pubmed: 37075126 ]
- 1b06 fab with nc99 ha trimer (Complex from Influenza A virus)
- Hemagglutinin ha2 chain (25 kDa, Protein from Influenza A virus)
- 1b06 light chain (11 kDa, Protein from Homo sapiens)
- Hemagglutinin ha1 chain (36 kDa, Protein from Influenza A virus)
- Cryo-em structure of the vrc321 clinical trial, vaccine-elicited, human antibody 1b06 in complex with a stabilized nc99 ha trimer (Complex)
- 1b06 heavy chain (13 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
CryoEM structure of monoclonal Fab 045-09 2B05 binding the lateral patch of influenza virus H1 HA
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7mem
Q-score: 0.425
Guthmiller JJ, Han J, Li L, Freyn AW, Liu STH, Stovicek O, Stamper CT, Dugan HL, Tepora ME, Utset HA, Bitar DJ, Hamel NJ, Changrob S, Zheng NY, Huang M, Krammer F, Nachbagauer R, Palese P, Ward AB, Wilson PC
Sci Transl Med (2021) 13 [ Pubmed: 34078743 DOI: doi:10.1126/scitranslmed.abg4535 ]
- Light chain of monoclonal antibody 045-09 2b05 (11 kDa, Protein from Homo sapiens)
- Cryoem structure of monoclonal fab 045-09 2b05 binding the lateral patch of h1 ha (Complex)
- Hemagglutinin (Complex from Influenza A virus (strain swl A/California/04/2009 H1N1))
- Hemagglutinin ha1 chain (36 kDa, Protein from Influenza A virus (strain swl A/California/04/2009 H1N1))
- Hemagglutinin ha2 chain (19 kDa, Protein from Influenza A virus (strain swl A/California/04/2009 H1N1))
- Monoclonal fab 045-09 2b05 (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Heavy chain of monoclonal antibody 045-09 2b05 (12 kDa, Protein from Homo sapiens)
CryoEM structure of influenza hemagglutinin A/Victoria/361/2011 in complex with cyno antibody 3B10
Resolution: 4.7 Å
EM Method: Single-particle
Fitted PDBs: 6wzt
Q-score: 0.315
Darricarrere N, Qiu Y, Kanekiyo M, Creanga A, Gillespie RA, Moin SM, Saleh J, Sancho J, Chou TH, Zhou Y, Zhang R, Dai S, Moody A, Saunders KO, Crank MC, Mascola JR, Graham BS, Wei CJ, Nabel GJ
Sci Transl Med (2021) 13 [ Pubmed: 33658355 DOI: doi:10.1126/scitranslmed.abe5449 ]
- Cyno antibody heavy chain (24 kDa, Protein from Macaca fascicularis)
- Influenza hemagglutinin a/victoria/361/2011 in complex with 3b10 fab (336 kDa, Complex from Influenza A virus)
- Hemagglutinin (56 kDa, Protein from Influenza A virus)
- Hemagglutinin (Complex from Macaca fascicularis)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Cyno antibody light chain (23 kDa, Protein from Macaca fascicularis)
- Cyno antibody (Complex)
Darricarrere N, Qiu Y, Kanekiyo M, Creanga A, Gillespie RA, Moin SM, Saleh J, Sancho J, Chou TH, Zhou Y, Zhang R, Dai S, Moody A, Saunders KO, Crank MC, Mascola JR, Graham BS, Wei CJ, Nabel GJ
Sci Transl Med (2021) 13 [ Pubmed: 33658355 DOI: doi:10.1126/scitranslmed.abe5449 ]
- Cyno antibody heavy chain (Protein from Macaca fascicularis)
- 1c4 fab (Complex from Macaca fascicularis)
- Influenza hemagglutinin a/vietnam/1203/2004 in complex with 1c4 fab (336 kDa, Complex)
- Hemagglutinin (Complex from Influenza A virus)
- Cyno antibody light chain (Protein from Macaca fascicularis)
- Influenza hemagglutinin (a/vietnam/1203/2004) (Protein from Influenza A virus)
CryoEM structure of influenza hemagglutinin A/Michigan/45/2015 in complex with cyno antibody 1C4
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 6xgc
Q-score: 0.392
Darricarrere N, Qiu Y, Kanekiyo M, Creanga A, Gillespie RA, Moin SM, Saleh J, Sancho J, Chou TH, Zhou Y, Zhang R, Dai S, Moody A, Saunders KO, Crank MC, Mascola JR, Graham BS, Wei CJ, Nabel GJ
Sci Transl Med (2021) 13 [ Pubmed: 33658355 DOI: doi:10.1126/scitranslmed.abe5449 ]
- Hemagglutinin (Complex from Influenza A virus (A/Michigan/45/2015(H1N1)))
- Hemagglutinin ha1 chain (36 kDa, Protein from Influenza A virus (A/Michigan/45/2015(H1N1)))
- 1c4 fab (Complex from Macaca fascicularis)
- 1c4 fab heavy chain (25 kDa, Protein from Macaca fascicularis)
- A/michigan/45/2015(h1n1) hemagglutinin in complex with 1c4 fab (320 MDa, Complex)
- Hemagglutinin ha2 chain (25 kDa, Protein from Influenza A virus (A/Michigan/45/2015(H1N1)))
- 1c4 fab light chain (22 kDa, Protein from Macaca fascicularis)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)