Term Information

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Accession
GO:0047545
Name
2-hydroxyglutarate dehydrogenase activity
Ontology
molecular_function
Synonyms
(S)-2-hydroxyglutarate:(acceptor) 2-oxidoreductase, (S)-2-hydroxyglutarate:acceptor 2-oxidoreductase, L-alpha-hydroxyglutarate dehydrogenase activity, alpha-hydroxyglutarate dehydrogenase activity, alpha-hydroxyglutarate oxidoreductase activity, hydroxyglutaric dehydrogenase activity, L-alpha-hydroxyglutarate:NAD+ 2-oxidoreductase, alpha-hydroxyglutarate dehydrogenase (NAD+ specific)
Alternate IDs
None
Definition
Catalysis of the reaction: (S)-2-hydroxyglutarate + acceptor = 2-oxoglutarate + reduced acceptor. Source: EC:1.1.99.2, MetaCyc:2-HYDROXYGLUTARATE-DEHYDROGENASE-RXN
Comment
None
History
See term history for GO:0047545 at QuickGO
Chem. react.
has participant hydrogen donor
has participant 2-oxoglutarate(2-)
has participant (S)-2-hydroxyglutarate(2-)
has participant hydrogen acceptor
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of 2-hydroxyglutarate dehydrogenase activity (GO:0047545)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
2-hydroxyglutarate dehydrogenase activity [RO:0000057 relation] RO:0000057  hydrogen donor (CHEBI:17499)
2-hydroxyglutarate dehydrogenase activity [is_a relation] is_a  oxidoreductase activity, acting on CH-OH group of donors (GO:0016614)
2-hydroxyglutarate dehydrogenase activity [RO:0000057 relation] RO:0000057  2-oxoglutarate(2-) (CHEBI:16810)
2-hydroxyglutarate dehydrogenase activity [RO:0000057 relation] RO:0000057  (S)-2-hydroxyglutarate(2-) (CHEBI:16782)
2-hydroxyglutarate dehydrogenase activity [RO:0000057 relation] RO:0000057  hydrogen acceptor (CHEBI:13193)
Children of 2-hydroxyglutarate dehydrogenase activity (GO:0047545)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
alpha-ketoglutarate reductase activity (GO:0061759) [is_a relation] is_a  2-hydroxyglutarate dehydrogenase activity
2-hydroxyglutarate dehydrogenase activity, forward reaction (GO:0061758) [is_a relation] is_a  2-hydroxyglutarate dehydrogenase activity