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Allotypes of IgM and IgD Receptors in the Mouse: A Probe for Lymphocyte Differentiation

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Contemporary Topics in Immunobiology

Abstract

In 1899, Metchnikoff proposed that macrophages might be studied using antimacrophage serum. The farsighted nature of this idea is indicated by the fact that virtually all the current methods for the study of lymphocyte surface receptors for antigen involve the use of antireceptor antisera. This somewhat circular approach (i.e., the use of antibodies to study antibodies) may be regarded as an example of the value of those methods of analysis which exploit biochemical affinities rather than classical chemistry.

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Author notes

  1. James W. Goding

    Present address: Department of Genetics, Stanford University School of Medicine, Stanford, California, USA

Authors and Affiliations

  1. The Waller and Eliza Hall Institute of Medical Research, The Royal Melbourne Hospital, Melbourne, Victoria, 3050, Australia

    James W. Goding

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Editors and Affiliations

  1. University of New Mexico, Albuquerque, New Mexico, USA

    Noel L. Warner

  2. University of Alabama in Birmingham, Birmingham, Alabama, USA

    Max D. Cooper

  3. Frederick Cancer Research Center, Frederick, Maryland, USA

    M. G. Hanna Jr.

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Goding, J.W. (1978). Allotypes of IgM and IgD Receptors in the Mouse: A Probe for Lymphocyte Differentiation. In: Warner, N.L., Cooper, M.D., Hanna, M.G. (eds) Contemporary Topics in Immunobiology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-0922-2_7

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  • DOI: https://doi.org/10.1007/978-1-4684-0922-2_7

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-0924-6

  • Online ISBN: 978-1-4684-0922-2

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