Abstract
The etiology of cancer is much wider than separately taken causal agent and rests against the most complicated interrelation and mutuality of many external and internal influences. Our researches with use of fluorescing antibodies to AFP, CEA and Ca-19-9 have shown that they are intensively besieged on a surface of cultivated malignant cells. It is the basic mechanism of tolerance and immunological escape, which is similar to pregnancy when «the maximal immunological most favored status” to developing fetus (semiallogenic transplant) is provided. The earliest revealing of first cancer cells, before steady community of cells and tumor angiogenesis were formed, has particular importance in the fight against cancer. The necessity of the specific completion of the weakened antineoplastic resistibility of people from high oncological risk groups is substantiated. The activity in this direction brought forth the design of embryonic anti-tumor modulator (EATM). EATM is composed of a wide pool of fetal proteins and proteoglycans isolated exceptionally from normal embryonic substances.
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References
Blokhin NN (1988) Shorthand record of assembly speech. Moscow, 53 p
Bachler K (1989) Earth radiation. Manchester, Wordmasters
Cohnheim JF (1877-1880-2) Vorlesungen uber ellgemine Pathologie. Berlin, Hirschwald, 691 p
Rosenthal S (1996) Cancer precursors and control by BCG. Dev Biol Stand 58:401–416
Mkrtchyan LN (2008) Embryonality and malignant growth: problems, creation of anticancer vaccine. New Armen Med J 2(1):36–55
Reya T, Morrison SJ, Clarke MF, Weissman IL (2001) Stem cells, cancer, and cancer stem cells. Nature 414:105–111
Li X, Lewis MT, Huang J, Gutierrez C, Osborne CK, Wu M-F, Hilsenbeck SG, Pavlick A, Zhang X, Chamness GC, Wong H, Rosen J, Chang JC (2008) Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy. JNCI 100:672–679
Sitko S, Mkrtchyan L (1994) Introduction to quantum medicine. Kiev, 127
Davidov MI, Zaridze DG, Lazarev MF (2007) Analysis of Russian population mortality causes. Her Russ Acad Med Sci 7:17–27
Jhukov NV (2007) From the editorial staff. Together Against Cancer 1(2):4–5
Strukov A, Gershanovich M, Filov V, Imyanitov E (2005) Problems of contemporary target therapy of malignant tumors. Voprosy Onkologii [Probl Oncol] 51(5):607–611
Medawar P, Hunt R (1983) Can fetal antigens be used for prophylactic immunization? Ciba Found Symp 96:160–181
Wilczynski JR (2006) Cancer and pregnancy share similar mechanisms of immunological escape. Chemotherapy 52:107–110
Russian Federation patent No. 2240810 (2004) Embryonic anti-tumour modulator of Mkrtchyan, mode of extraction and application
Linheng L, Neaves WB (2006) Normal stem cells and cancer stem cells: the niche matters. Cancer Res 66(9):4553–4557
Rowan K (2009) Are cancer stem cells real? After four decades, debate still simmers. JNCI 101(8):546–547
Mkrtchyan LN (2007) Vaccines and vaccination. New Armen Med J 1(1):75–78
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Special issue article in honor of Professor Armen Galoyan.
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Mkrtchyan, L.N. On a New Strategy of Preventive Oncology. Neurochem Res 35, 868–874 (2010). https://doi.org/10.1007/s11064-009-0110-x
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DOI: https://doi.org/10.1007/s11064-009-0110-x