Cell
Volume 29, Issue 1, May 1982, Pages 161-169
Article
Isolation of a transforming sequence from a human bladder carcinoma cell line
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Cited by (605)
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Ras and Ras Signaling as a Therapeutic Target in Cancer
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Two-phased evolution: Genome chaos-mediated information creation and maintenance
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RAS mutations in human cancers: Roles in precision medicine
2019, Seminars in Cancer BiologyCitation Excerpt :Levingson's group used HiHi3 to clone human KRAS sequence [28]. In Early 1982, human transforming genes were cloned from T24 and EJ bladder carcinoma cell lines and reported independently by Weinberg, Wigler and Barbacid laboratories [29–31]. The molecular nature of these human oncogenes was resolved when Channing Der used retroviral probes to hybridize DNA isolated from NIH-3T3 cells which had been transformed with various human tumor DNAs [32].
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Present address: Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts 02114.
Copyright © 1982