Thiopurine analogs and mycophenolic acid synergistically inhibit the papain-like protease of Middle East respiratory syndrome coronavirus
Abbreviations
AFC
7-amino-4-trifluoro-methylcoumarin
CoV
coronavirus
DUB
deubiquitination
MERS
Middle East respiratory syndrome
6MP
6-mercaptopurine
NEM
N-ethylmaleimide
PLpro
papain-like protease
SARS
severe acute respiratory syndrome
6TG
6-thioguanine
Ub
ubiquitin
Keywords
MERS-CoV papain-like protease
6-Mercaptopurine
6-Thioguanine
Mycophenolic acid
Synergistic inhibition
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