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Abstract

A recent dispersal of modern humans out of Africa is now widely accepted, but the routes taken across Eurasia are still disputed. We show that mitochondrial DNA variation in isolated “relict” populations in southeast Asia supports the view that there was only a single dispersal from Africa, most likely via a southern coastal route, through India and onward into southeast Asia and Australasia. There was an early offshoot, leading ultimately to the settlement of the Near East and Europe, but the main dispersal from India to Australia ∼65,000 years ago was rapid, most likely taking only a few thousand years.

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Supported by United Productions and the Discovery Channel, the British Academy, the Royal Society, the University of Huddersfield, the Wellcome Trust, the Italian Ministry of the University (Progetti Ricerca Interesse Nazionale 2003), Progetto CNR-MIUR Genomica Funzionale-Legge 449/97, Grandi Progetti di Ateneo (Università La Sapienza), the Muzium Negara Malaysia (Kuala Lumpur), and the Universiti Putra Malaysia. We thank the Malaysian participants for providing cheek-swab samples and J. Clegg and A. S. Sofro for Indonesian samples.

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Published In

Science
Volume 308 | Issue 5724
13 May 2005

Submission history

Received: 14 January 2005
Accepted: 24 March 2005
Published in print: 13 May 2005

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Notes

Supporting Online Material
www.sciencemag.org/cgi/content/full/308/5724/1034/DC1
Materials and Methods
Fig. S1
Tables S1 to S4
References

Authors

Affiliations

Vincent Macaulay* [email protected]
Department of Statistics, University of Glasgow, Glasgow G12 8QQ, Scotland, UK.
Catherine Hill
Department of Chemical and Biological Sciences, University of Huddersfield, Huddersfield HD1 3DH, UK.
Alessandro Achilli
Dipartimento di Genetica e Microbiologia, Università di Pavia, 27100 Pavia, Italy.
Chiara Rengo
Dipartimento di Genetica e Microbiologia, Università di Pavia, 27100 Pavia, Italy.
Douglas Clarke
Department of Chemical and Biological Sciences, University of Huddersfield, Huddersfield HD1 3DH, UK.
William Meehan
Department of Chemical and Biological Sciences, University of Huddersfield, Huddersfield HD1 3DH, UK.
James Blackburn
Department of Chemical and Biological Sciences, University of Huddersfield, Huddersfield HD1 3DH, UK.
Ornella Semino
Dipartimento di Genetica e Microbiologia, Università di Pavia, 27100 Pavia, Italy.
Rosaria Scozzari
Dipartimento di Genetica e Biologia Molecolare, Università “La Sapienza,” 00185 Roma, Italy.
Fulvio Cruciani
Dipartimento di Genetica e Biologia Molecolare, Università “La Sapienza,” 00185 Roma, Italy.
Adi Taha
National Museum of Kuala Lumpur, 50566 Kuala Lumpur, Malaysia.
Norazila Kassim Shaari
Department of Biomedical Science, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia.
Joseph Maripa Raja
Department of Biomedical Science, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia.
Patimah Ismail
Department of Biomedical Science, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia.
Zafarina Zainuddin
Department of Forensic Medicine and Science, University of Glasgow, Glasgow G12 8QQ, Scotland, UK.
William Goodwin
Department of Forensic and Investigative Science, University of Central Lancashire, Preston PR1 2HE, UK.
David Bulbeck
School of Archaeology and Anthropology, Australian National University, Canberra, ACT 0200, Australia.
Hans-Jürgen Bandelt
Department of Mathematics, University of Hamburg, 20146 Hamburg, Germany.
Stephen Oppenheimer
Department of Anthropology, University of Oxford, Oxford OX1 2JD, UK.
Antonio Torroni
Dipartimento di Genetica e Microbiologia, Università di Pavia, 27100 Pavia, Italy.
Martin Richards* [email protected]
Schools of Biology and Computing, University of Leeds, Leeds LS2 9JT, UK.

Notes

*
To whom correspondence should be addressed. E-mail: [email protected]; [email protected]

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