IMR Press / FBS / Volume 4 / Issue 1 / DOI: 10.2741/s253

Frontiers in Bioscience-Scholar (FBS) is published by IMR Press from Volume 13 Issue 1 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.

Review

Diet, obesity and breast cancer: an update

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1 Department of Surgery, General Surgery and Breast Unit, University of Catania, Italy
2 Department of Surgery, Transplantation and Advanced Technologies, University of Catania, Italy
3 Department of Medical Oncology - National Cancer Institute - I.R.C.C.S. Aviano, PN
4 Department of Biochemistry, Medical Chemistry and Molecular Biology, University of Catania, Italy
5 Division of Pathology, National Cancer Institute - I.R.C.C.S. Aviano, PN
6 Division of Laparoscopic and Bariatric Surgery, University of Maryland, Baltimore, MD USA

*Author to whom correspondence should be addressed.

 

Front. Biosci. (Schol Ed) 2012, 4(1), 90–108; https://doi.org/10.2741/s253
Published: 1 January 2012
Abstract

Numerous studies indagated the relationship between dietary pattern or specific nutrients and breast cancer (BC) risk and survival. Different ethnic o social groups show differences in breast cancer incidence that could be explained by different dietary patterns. Furthermore, many nutrients could reasonably increase the risk of cancer because of their content of carcinogens or their precursors as well as of promoting substances. However, the only convincing evidences linking life style to increased BC risk are related to obesity and moderate intake of alcohol and limited to postmenopause. Saturated fat, red meat, high temperature cooking have been indicated as possible risk factors, but adjusted analyses have not confirmed this association or have limited the relationship to specific subgroups. Even the protective effect of fiber, fruit, vegetables and phytoestrogens has been suggested but not definitively demonstrated. Thus, healthy dietary patterns, with abstention from alcohol and weight control, reduce the risk of cancer or at least improve the survival of affected women by reducing the incidence of comorbidities.


Keywords
Breast Neoplasms
Epidemiology
Etiology
Prevention
Control
Body Weight
Diet
Food Habits
Review
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