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ENZYME

ENZYME entry: EC 1.1.1.136

Accepted Name
UDP-N-acetylglucosamine 6-dehydrogenase
Alternative Name(s)
UDP-2-acetamido-2-deoxy-D-glucose:NAD oxidoreductase
Reaction catalysed
H2O + 2 NAD(+) + UDP-N-acetyl-alpha-D-glucosamine <=> 3 H(+) + 2 NADH + UDP-N-2-acetamido-2-deoxy-alpha-D-glucuronate
Comment(s)
This enzyme participates in the biosynthetic pathway for UDP-alpha-D- ManNAc3NAcA (UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-mannuronic acid), an important precursor of B-band lipopolysaccharide.
Cross-references
BRENDA 1.1.1.136
EC2PDB 1.1.1.136
ExplorEnz 1.1.1.136
PRIAM enzyme-specific profiles 1.1.1.136
KEGG Ligand Database for Enzyme Nomenclature 1.1.1.136
IUBMB Enzyme Nomenclature 1.1.1.136
IntEnz 1.1.1.136
MEDLINE Find literature relating to 1.1.1.136
MetaCyc 1.1.1.136
Rhea expert-curated reactions 1.1.1.136
UniProtKB/Swiss-Prot
G3XD94, UGND_PSEAE

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