Expasy logo

ENZYME

ENZYME entry: EC 1.1.1.189

Accepted Name
prostaglandin-E2 9-reductase
Alternative Name(s)
9-keto-prostaglandin E2 reductase
9-ketoprostaglandin reductase
PGE2 9-ketoreductase
PGE2 9-oxoreductase
prostaglandin-E2 9-oxoreductase
Reaction catalysed
NADP(+) + prostaglandin F2alpha <=> H(+) + NADPH + prostaglandin E2
Comment(s)
  • Reduces prostaglandin E2 to prostaglandin F2alpha.
  • A number of other 9-oxo- and 15-oxo-prostaglandin derivatives can also be reduced to the corresponding hydroxy compounds.
  • May be identical with EC 1.1.1.197.
Cross-references
BRENDA 1.1.1.189
EC2PDB 1.1.1.189
ExplorEnz 1.1.1.189
PRIAM enzyme-specific profiles 1.1.1.189
KEGG Ligand Database for Enzyme Nomenclature 1.1.1.189
IUBMB Enzyme Nomenclature 1.1.1.189
IntEnz 1.1.1.189
MEDLINE Find literature relating to 1.1.1.189
MetaCyc 1.1.1.189
Rhea expert-curated reactions 1.1.1.189
UniProtKB/Swiss-Prot
Q3SZD7, CBR1_BOVIN P16152, CBR1_HUMAN Q8MI29, CBR1_MACFA
P48758, CBR1_MOUSE Q28960, CBR1_PIG Q5RCU5, CBR1_PONAB
P47844, CBR1_RABIT P47727, CBR1_RAT P80508, PE2R_RABIT

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-