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ENZYME

ENZYME entry: EC 1.1.1.21

Accepted Name
aldose reductase
Alternative Name(s)
aldehyde reductase
polyol dehydrogenase (NADP(+))
Reaction catalysed
  • an alditol + NAD(+) <=> an aldose + H(+) + NADH
  • an alditol + NADP(+) <=> an aldose + H(+) + NADPH
Comment(s)
  • Wide specificity.
  • Formerly EC 1.1.1.139.
Cross-references
BRENDA 1.1.1.21
EC2PDB 1.1.1.21
ExplorEnz 1.1.1.21
PRIAM enzyme-specific profiles 1.1.1.21
KEGG Ligand Database for Enzyme Nomenclature 1.1.1.21
IUBMB Enzyme Nomenclature 1.1.1.21
IntEnz 1.1.1.21
MEDLINE Find literature relating to 1.1.1.21
MetaCyc 1.1.1.21
Rhea expert-curated reactions 1.1.1.21
UniProtKB/Swiss-Prot
P21300, ALD1_MOUSE Q5RJP0, ALD1_RAT O08782, ALD2_CRIGR
P45377, ALD2_MOUSE P16116, ALDR_BOVIN Q8SSK6, ALDR_ENCCU
P23901, ALDR_HORVU P15121, ALDR_HUMAN P45376, ALDR_MOUSE
P80276, ALDR_PIG P15122, ALDR_RABIT P07943, ALDR_RAT
Q6IMN8, ALRA_DICDI Q54NZ7, ALRB_DICDI Q55FL3, ALRC_DICDI
P38715, GRE3_YEAST

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.-.-
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