Expasy logo

ENZYME

ENZYME entry: EC 1.1.1.3

Accepted Name
homoserine dehydrogenase
Reaction catalysed
  • L-homoserine + NAD(+) <=> H(+) + L-aspartate 4-semialdehyde + NADH
  • L-homoserine + NADP(+) <=> H(+) + L-aspartate 4-semialdehyde + NADPH
Comment(s)
  • The enzyme from Saccharomyces cerevisiae acts most rapidly with NAD(+); the Neurospora enzyme with NADP(+).
  • The enzyme from Escherichia coli is a multifunctional protein, which also catalyzes the reaction of EC 2.7.2.4.
Cross-references
BRENDA 1.1.1.3
EC2PDB 1.1.1.3
ExplorEnz 1.1.1.3
PRIAM enzyme-specific profiles 1.1.1.3
KEGG Ligand Database for Enzyme Nomenclature 1.1.1.3
IUBMB Enzyme Nomenclature 1.1.1.3
IntEnz 1.1.1.3
MEDLINE Find literature relating to 1.1.1.3
MetaCyc 1.1.1.3
Rhea expert-curated reactions 1.1.1.3
UniProtKB/Swiss-Prot
P00561, AK1H_ECOLI P27725, AK1H_SERMA P00562, AK2H_ECOLI
Q9SA18, AKH1_ARATH P49079, AKH1_MAIZE O81852, AKH2_ARATH
P49080, AKH2_MAIZE P57290, AKH_BUCAI Q8K9U9, AKH_BUCAP
Q89AR4, AKH_BUCBP P37142, AKH_DAUCA P44505, AKH_HAEIN
P19582, DHOM_BACSU P08499, DHOM_CORGL Q5B998, DHOM_EMENI
Q9ZL20, DHOM_HELPJ P56429, DHOM_HELPY Q9CGD8, DHOM_LACLA
P52985, DHOM_LACLC P37143, DHOM_METGL Q58997, DHOM_METJA
P63630, DHOM_MYCBO P46806, DHOM_MYCLE P9WPX0, DHOM_MYCTO
P9WPX1, DHOM_MYCTU Q5F8J4, DHOM_NEIG1 P29365, DHOM_PSEAE
O94671, DHOM_SCHPO P52986, DHOM_SYNY3 P31116, DHOM_YEAST
P37144, DHON_METGL

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-