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ENZYME

ENZYME entry: EC 1.1.1.309

Accepted Name
phosphonoacetaldehyde reductase (NADH)
Reaction catalysed
2-hydroxyethylphosphonate + NAD(+) <=> H(+) + NADH + phosphonoacetaldehyde
Comment(s)
  • The enzyme from Streptomyces viridochromogenes catalyzes a step in the biosynthesis of phosphinothricin tripeptide, the reduction of phosphonoacetaldehyde to 2-hydroxyethylphosphonate.
  • The preferred cofactor is NADH, lower activity with NADPH.
Cross-references
BRENDA 1.1.1.309
EC2PDB 1.1.1.309
ExplorEnz 1.1.1.309
PRIAM enzyme-specific profiles 1.1.1.309
KEGG Ligand Database for Enzyme Nomenclature 1.1.1.309
IUBMB Enzyme Nomenclature 1.1.1.309
IntEnz 1.1.1.309
MEDLINE Find literature relating to 1.1.1.309
MetaCyc 1.1.1.309
Rhea expert-curated reactions 1.1.1.309
UniProtKB/Swiss-Prot
D9XF45, PHPC_STRVT

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