ENZYME entry: EC 1.1.1.329

Accepted Name

2-deoxy-scyllo-inosamine dehydrogenase

Reaction catalysed

2-deoxy-scyllo-inosamine + NADP(+) <=> 3-amino-2,3-dideoxy-scyllo-inosose + H(+) + NADPH
2-deoxy-scyllo-inosamine + NAD(+) <=> 3-amino-2,3-dideoxy-scyllo-inosose + H(+) + NADH

Comment(s)

Involved in the biosynthetic pathways of several clinically important aminocyclitol antibiotics, including kanamycin, neomycin and ribostamycin. cf. EC 1.1.99.38.

Cross-references

BRENDA

1.1.1.329

EC2PDB

1.1.1.329

ExplorEnz

1.1.1.329

PRIAM enzyme-specific profiles

1.1.1.329

KEGG Ligand Database for Enzyme Nomenclature

1.1.1.329

IUBMB Enzyme Nomenclature

1.1.1.329

IntEnz

1.1.1.329

MEDLINE

Find literature relating to 1.1.1.329

MetaCyc

1.1.1.329

Rhea expert-curated reactions

1.1.1.329

UniProtKB/Swiss-Prot

Q70KF0, DOIAD_MICEC	Q2MFP3, DOIAD_STREY	Q53U21, DOIAD_STRFR
Q6L743, DOIAD_STRKN	Q2MF72, DOIAD_STRLV	Q4R0W1, DOIAD_STRRI
Q2MF22, DOIAD_STRSD

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