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ENZYME

ENZYME entry: EC 1.1.1.96

Accepted Name
diiodophenylpyruvate reductase
Reaction catalysed
3-(3,5-diiodo-4-hydroxyphenyl)lactate + NAD(+) <=> 3-(3,5-diiodo-4-hydroxyphenyl)pyruvate + H(+) + NADH
Comment(s)
  • Substrates contain an aromatic ring with a pyruvate side chain.
  • The most active substrates are halogenated derivatives.
  • Compounds with hydroxy or amino groups in the 3 or 5 position are inactive.
Cross-references
BRENDA 1.1.1.96
EC2PDB 1.1.1.96
ExplorEnz 1.1.1.96
PRIAM enzyme-specific profiles 1.1.1.96
KEGG Ligand Database for Enzyme Nomenclature 1.1.1.96
IUBMB Enzyme Nomenclature 1.1.1.96
IntEnz 1.1.1.96
MEDLINE Find literature relating to 1.1.1.96
MetaCyc 1.1.1.96
Rhea expert-curated reactions 1.1.1.96
UniProtKB/Swiss-Prot
Q3T145, MDHC_BOVIN Q7YRU4, MDHC_FELCA P40925, MDHC_HUMAN
P14152, MDHC_MOUSE P11708, MDHC_PIG O88989, MDHC_RAT

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