ENZYME entry: EC 1.1.99.27

Accepted Name
(R)-pantolactone dehydrogenase (flavin)
Alternative Name(s)
(R)-pantoyllactone dehydrogenase (flavin)
2-dehydropantolactone reductase (flavin)
2-dehydropantoyl-lactone reductase (flavin)
Reaction catalysed
(R)-pantolactone + A <=> 2-dehydropantolactone + AH2
Comment(s)
High specificity for (R)-pantolactone. Phenazine methosulfate (PMS) can act as acceptor. The enzyme has been studied in Nocardia asteroides and shown to be membrane-bound and induced by 1,2-propanediol.
Cross-references
BRENDA	1.1.99.27
EC2PDB	1.1.99.27
ExplorEnz	1.1.99.27
PRIAM enzyme-specific profiles	1.1.99.27
KEGG Ligand Database for Enzyme Nomenclature	1.1.99.27
IUBMB Enzyme Nomenclature	1.1.99.27
IntEnz	1.1.99.27
MEDLINE	Find literature relating to 1.1.99.27
MetaCyc	1.1.99.27
Rhea expert-curated reactions	1.1.99.27

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