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ENZYME

ENZYME entry: EC 1.1.99.38

Accepted Name
2-deoxy-scyllo-inosamine dehydrogenase (AdoMet-dependent)
Reaction catalysed
2-deoxy-scyllo-inosamine + S-adenosyl-L-methionine <=> 3-amino-2,3-dideoxy-scyllo-inosose + 5'-deoxyadenosine + H(+) + L-methionine
Comment(s)
  • Involved in the biosynthetic pathway of the aminoglycoside antibiotics of the butirosin family.
  • The enzyme from Bacillus circulans was shown to be a radical S-adenosyl-L-methionine (SAM) enzyme. cf. EC 1.1.1.329.
Cross-references
BRENDA 1.1.99.38
EC2PDB 1.1.99.38
ExplorEnz 1.1.99.38
PRIAM enzyme-specific profiles 1.1.99.38
KEGG Ligand Database for Enzyme Nomenclature 1.1.99.38
IUBMB Enzyme Nomenclature 1.1.99.38
IntEnz 1.1.99.38
MEDLINE Find literature relating to 1.1.99.38
MetaCyc 1.1.99.38
Rhea expert-curated reactions 1.1.99.38
UniProtKB/Swiss-Prot
Q8G907, BTRN_NIACI

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