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ENZYME

ENZYME entry: EC 1.11.1.12

Accepted Name
phospholipid-hydroperoxide glutathione peroxidase
Alternative Name(s)
peroxidation-inhibiting protein
Reaction catalysed
a hydroperoxy polyunsaturated fatty acid + 2 glutathione <=> a hydroxy polyunsaturated fatty acid + glutathione disulfide + H2O
Comment(s)
The products of action of EC 1.13.11.12 on phospholipids can act as acceptor; H2O2 can also act, but much more slowly (cf. EC 1.11.1.9).
Cross-references
BRENDA 1.11.1.12
EC2PDB 1.11.1.12
ExplorEnz 1.11.1.12
PRIAM enzyme-specific profiles 1.11.1.12
KEGG Ligand Database for Enzyme Nomenclature 1.11.1.12
IUBMB Enzyme Nomenclature 1.11.1.12
IntEnz 1.11.1.12
MEDLINE Find literature relating to 1.11.1.12
MetaCyc 1.11.1.12
Rhea expert-curated reactions 1.11.1.12
UniProtKB/Swiss-Prot
P52032, GPX1_ARATH P00435, GPX1_BOVIN Q0EF99, GPX1_CALJA
P07203, GPX1_HUMAN Q865R2, GPX1_MACFU P11352, GPX1_MOUSE
Q0EFA0, GPX1_PANTR O24296, GPX1_PEA Q8MJ14, GPX1_PIG
Q4AEI3, GPX1_PONPY P11909, GPX1_RABIT P04041, GPX1_RAT
Q4AEI1, GPX1_SAPAP Q0EF98, GPX2_CALJA P18283, GPX2_HUMAN
Q4AEH9, GPX2_HYLLA Q4AEH8, GPX2_MACFU Q9JHC0, GPX2_MOUSE
Q4AEI0, GPX2_PONPY P83645, GPX2_RAT Q4AEH7, GPX2_SAPAP
Q9N2J2, GPX4_BOVIN Q32QL6, GPX4_CALJA Q06652, GPX4_CITSI
O49069, GPX4_GOSHI O23968, GPX4_HELAN P36969, GPX4_HUMAN
Q4AEH1, GPX4_HYLLA Q4AEH0, GPX4_MACFU Q9LEF0, GPX4_MESCR
O70325, GPX4_MOUSE P30708, GPX4_NICSY P36968, GPX4_PIG
Q4AEH2, GPX4_PONPY P36970, GPX4_RAT Q4AEG9, GPX4_SAPAP
O24031, GPX4_SOLLC O23814, GPX4_SPIOL Q9FXS3, GPX4_TOBAC
O48646, GPX6_ARATH Q8SSH7, GPX_ENCCU

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.11.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.11.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-