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ENZYME

ENZYME entry: EC 1.2.1.51

Accepted Name
pyruvate dehydrogenase (NADP(+))
Alternative Name(s)
pyruvate:NADP(+) oxidoreductase
Reaction catalysed
CoA + NADP(+) + pyruvate <=> acetyl-CoA + CO2 + NADPH
Comment(s)
  • The Euglena enzyme can also use FAD or methylviologen as acceptor, more slowly.
  • Inhibited by oxygen.
Cross-references
BRENDA 1.2.1.51
EC2PDB 1.2.1.51
ExplorEnz 1.2.1.51
PRIAM enzyme-specific profiles 1.2.1.51
KEGG Ligand Database for Enzyme Nomenclature 1.2.1.51
IUBMB Enzyme Nomenclature 1.2.1.51
IntEnz 1.2.1.51
MEDLINE Find literature relating to 1.2.1.51
MetaCyc 1.2.1.51
Rhea expert-curated reactions 1.2.1.51
UniProtKB/Swiss-Prot
Q968X7, PNO_CRYPV Q94IN5, PNO_EUGGR

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