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ENZYME

ENZYME entry: EC 1.2.1.64

Accepted Name
4-hydroxybenzaldehyde dehydrogenase (NAD(+))
Alternative Name(s)
4-hydroxybenzaldehyde dehydrogenase
p-hydroxybenzaldehyde dehydrogenase
Reaction catalysed
4-hydroxybenzaldehyde + H2O + NAD(+) <=> 4-hydroxybenzoate + 2 H(+) + NADH
Comment(s)
  • The bacterial enzyme (characterized from an unidentified denitrifying bacterium) is involved in an anaerobic toluene degradation pathway.
  • The plant enzyme is involved in formation of 4-hydroxybenzoate, a cell wall-bound phenolic acid that plays a major role in plant defense against pathogens. cf. EC 1.2.1.96.
Cross-references
BRENDA 1.2.1.64
EC2PDB 1.2.1.64
ExplorEnz 1.2.1.64
PRIAM enzyme-specific profiles 1.2.1.64
KEGG Ligand Database for Enzyme Nomenclature 1.2.1.64
IUBMB Enzyme Nomenclature 1.2.1.64
IntEnz 1.2.1.64
MEDLINE Find literature relating to 1.2.1.64
MetaCyc 1.2.1.64
Rhea expert-curated reactions 1.2.1.64
UniProtKB/Swiss-Prot
Q04458, HFD1_YEAST Q8NMB0, VDH_CORGL

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