Expasy logo

ENZYME

ENZYME entry: EC 1.2.7.8

Accepted Name
indolepyruvate ferredoxin oxidoreductase
Alternative Name(s)
3-(indol-3-yl)pyruvate synthase (ferredoxin)
IOR
Reaction catalysed
CoA + indole-3-pyruvate + 2 oxidized [2Fe-2S]-[ferredoxin] <=> (indol-3-yl)acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]
Comment(s)
  • Preferentially utilizes the transaminated forms of aromatic amino acids and can use phenylpyruvate and 4-hydroxyphenylpyruvate as substrates.
  • This enzyme, which is found in archaea, is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.
  • For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7.
Cross-references
BRENDA 1.2.7.8
EC2PDB 1.2.7.8
ExplorEnz 1.2.7.8
PRIAM enzyme-specific profiles 1.2.7.8
KEGG Ligand Database for Enzyme Nomenclature 1.2.7.8
IUBMB Enzyme Nomenclature 1.2.7.8
IntEnz 1.2.7.8
MEDLINE Find literature relating to 1.2.7.8
MetaCyc 1.2.7.8
Rhea expert-curated reactions 1.2.7.8
UniProtKB/Swiss-Prot
O28783, IORA_ARCFU O27880, IORA_METTH P80910, IORA_METTM
Q9UZ57, IORA_PYRAB O58495, IORA_PYRHO O07835, IORA_THEKO
O28249, IORB_ARCFU O27881, IORB_METTH P80911, IORB_METTM
Q9UZ56, IORB_PYRAB O58496, IORB_PYRHO O07836, IORB_THEKO

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.2.7.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-