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ENZYME

ENZYME entry: EC 1.3.99.23

Accepted Name
all-trans-retinol 13,14-reductase
Alternative Name(s)
(13,14)-all-trans-retinol saturase
retinol saturase
RetSat
Reaction catalysed
A + all-trans-13,14-dihydroretinol <=> AH2 + all-trans-retinol
Comment(s)
  • The reaction is only known to occur in the opposite direction to that given above, with the enzyme being specific for all-trans-retinol as substrate.
  • Neither all-trans-retinoic acid nor 9-cis, 11-cis or 13-cis-retinol isomers are substrates.
  • May play a role in the metabolism of vitamin A.
Cross-references
BRENDA 1.3.99.23
EC2PDB 1.3.99.23
ExplorEnz 1.3.99.23
PRIAM enzyme-specific profiles 1.3.99.23
KEGG Ligand Database for Enzyme Nomenclature 1.3.99.23
IUBMB Enzyme Nomenclature 1.3.99.23
IntEnz 1.3.99.23
MEDLINE Find literature relating to 1.3.99.23
MetaCyc 1.3.99.23
Rhea expert-curated reactions 1.3.99.23
UniProtKB/Swiss-Prot
Q5BLE8, RETST_DANRE Q6NUM9, RETST_HUMAN Q64FG0, RETST_MACFA
Q64FW2, RETST_MOUSE Q8VHE9, RETST_RAT

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