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ENZYME

ENZYME entry: EC 1.5.1.21

Accepted Name
1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase (NADPH)
Alternative Name(s)
Delta(1)-piperideine-2-carboxylate reductase
Pyr2C reductase
Reaction catalysed
  • L-pipecolate + NADP(+) <=> Delta(1)-piperideine-2-carboxylate + H(+) + NADPH
  • L-proline + NADP(+) <=> 1-pyrroline-2-carboxylate + H(+) + NADPH
Comment(s)
  • The enzyme is involved in the catabolism of D-lysine and D-proline in bacteria that belong to the Pseudomonas genus.
  • In contrast to EC 1.5.1.1, which shows similar activity with NADPH and NADH, this enzyme is specific for NADPH.
  • Formerly EC 1.5.1.14.
Cross-references
BRENDA 1.5.1.21
EC2PDB 1.5.1.21
ExplorEnz 1.5.1.21
PRIAM enzyme-specific profiles 1.5.1.21
KEGG Ligand Database for Enzyme Nomenclature 1.5.1.21
IUBMB Enzyme Nomenclature 1.5.1.21
IntEnz 1.5.1.21
MEDLINE Find literature relating to 1.5.1.21
MetaCyc 1.5.1.21
Rhea expert-curated reactions 1.5.1.21
UniProtKB/Swiss-Prot
Q9I492, PY2CR_PSEAE Q5FB93, PY2CR_PSEPU Q4U331, PY2CR_PSEUB

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.5.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-