Expasy logo

ENZYME

ENZYME entry: EC 1.6.5.9

Accepted Name
NADH:ubiquinone reductase (non-electrogenic)
Alternative Name(s)
coenzyme Q reductase
electron transfer complex I
NADH2 dehydrogenase (ubiquinone)
NADH-coenzyme Q oxidoreductase
NADH-coenzyme Q reductase
NADH-CoQ oxidoreductase
NADH-CoQ reductase
NADH-Q6 oxidoreductase
NADH-ubiquinone oxidoreductase
NADH-ubiquinone reductase
ubiquinone reductase
Reaction catalysed
a quinone + H(+) + NADH <=> a quinol + NAD(+)
Comment(s)
  • A flavoprotein (FAD or FMN).
  • Occurs in mitochondria of yeast and plants, and in aerobic bacteria.
  • Has low activity with NADPH.
  • Unlike EC 7.1.1.2, this enzyme does not pump proteons of sodium ions across the membrane.
  • It is also not sensitive to rotenone.
  • Formerly EC 1.6.5.11.
Cross-references
BRENDA 1.6.5.9
EC2PDB 1.6.5.9
ExplorEnz 1.6.5.9
PRIAM enzyme-specific profiles 1.6.5.9
KEGG Ligand Database for Enzyme Nomenclature 1.6.5.9
IUBMB Enzyme Nomenclature 1.6.5.9
IntEnz 1.6.5.9
MEDLINE Find literature relating to 1.6.5.9
MetaCyc 1.6.5.9
Rhea expert-curated reactions 1.6.5.9
UniProtKB/Swiss-Prot
M1BYJ7, ENDB1_SOLTU M0ZYF3, INDA1_SOLTU Q8GWA1, NDA1_ARATH
Q9ST63, NDA1_SOLTU O80874, NDA2_ARATH Q1JPL4, NDB1_ARATH
Q9ST62, NDB1_SOLTU Q94BV7, NDB2_ARATH F4JJJ3, NDB3_ARATH
Q9SKT7, NDB4_ARATH Q8GXR9, NDC1_ARATH O14121, NDH1_SCHPO
P40215, NDH1_YEAST O43090, NDH2_SCHPO F2Z699, NDH2_YARLI
Q07500, NDH2_YEAST P95200, NDHA_MYCTU P00393, NDH_ECOLI
P44856, NDH_HAEIN P95160, NDH_MYCTU Q2FID4, NDH_STAA3
Q2FZV7, NDH_STAA8 Q2YWP9, NDH_STAAB Q5HHE4, NDH_STAAC
Q99VE0, NDH_STAAM Q7A6J4, NDH_STAAN Q6GIE7, NDH_STAAR
Q6GAY5, NDH_STAAS Q8NXG0, NDH_STAAW Q5HQM1, NDH_STAEQ
Q8CPV5, NDH_STAES Q4L4V6, NDH_STAHJ Q49W80, NDH_STAS1
P32340, NDI1_YEAST Q9I4V0, NQRED_PSEAE

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.6.5.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.6.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-