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ENZYME

ENZYME entry: EC 4.1.1.28

Accepted Name
aromatic-L-amino-acid decarboxylase
Alternative Name(s)
5-hydroxytryptophan decarboxylase
aromatic amino acid decarboxylase
DOPA decarboxylase
hydroxytryptophan decarboxylase
L-DOPA decarboxylase
tryptophan decarboxylase
Reaction catalysed
  • H(+) + L-dopa <=> CO2 + dopamine
  • 5-hydroxy-L-tryptophan + H(+) <=> CO2 + serotonin
Comment(s)
  • Also acts on other aromatic L-amino acids, including L-tryptophan.
  • Formerly EC 4.1.1.26 and EC 4.1.1.27.
Cross-references
BRENDA 4.1.1.28
EC2PDB 4.1.1.28
ExplorEnz 4.1.1.28
PRIAM enzyme-specific profiles 4.1.1.28
KEGG Ligand Database for Enzyme Nomenclature 4.1.1.28
IUBMB Enzyme Nomenclature 4.1.1.28
IntEnz 4.1.1.28
MEDLINE Find literature relating to 4.1.1.28
MetaCyc 4.1.1.28
Rhea expert-curated reactions 4.1.1.28
UniProtKB/Swiss-Prot
I0DFJ0, AADC_BACAT P27718, DDC_BOVIN P34751, DDC_CAEEL
P22781, DDC_CAVPO O96571, DDC_DROLE P05031, DDC_DROME
O96567, DDC_DROSI P20711, DDC_HUMAN P48861, DDC_MANSE
O88533, DDC_MOUSE P80041, DDC_PIG P14173, DDC_RAT
Q6ZJK7, TDC1_ORYSJ P17770, TDC_CATRO P54768, TYDC1_PAPSO
P54769, TYDC2_PAPSO P54770, TYDC3_PAPSO P54771, TYDC5_PAPSO

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-