Abstract
Flagellin, the main protein of the bacterial flagella, elicits defence responses and alters growth in Arabidopsis seedlings. Previously, we identified the FLS1 locus, which confers flagellin insensitivity in Ws-0. To identify additional components involved in flagellin perception, we screened for flagellin insensitivity mutants in the flagellin-sensitive accession La-er. Here, we describe the identification of a new locus, FLS2, by a map-based strategy. The FLS2 gene is ubiquitously expressed and encodes a putative receptor kinase. FLS2 shares structural and functional homologies with known plant resistance genes and with components involved in the innate immune system of mammals and insects.
Publication types
- Research Support, Non-U.S. Gov't
MeSH terms
- Amino Acid Sequence
- Arabidopsis / drug effects*
- Arabidopsis / enzymology*
- Arabidopsis / genetics
- Arabidopsis / growth & development
- Arabidopsis Proteins*
- Cloning, Molecular
- Flagellin / pharmacology*
- Gene Expression Profiling
- Genes, Plant / genetics
- Genetic Complementation Test
- Leucine-Rich Repeat Proteins
- Membrane Proteins / chemistry
- Membrane Proteins / genetics
- Membrane Proteins / metabolism
- Molecular Sequence Data
- Mutation / genetics
- Phenotype
- Plant Proteins / chemistry
- Plant Proteins / genetics
- Plant Proteins / metabolism
- Plants, Genetically Modified
- Protein Kinases / chemistry
- Protein Kinases / genetics
- Protein Kinases / metabolism*
- Proteins / chemistry
- Proteins / genetics
- Proteins / metabolism*
- RNA, Messenger / genetics
- RNA, Messenger / metabolism
- Respiratory Burst
- Signal Transduction / drug effects
Substances
- Arabidopsis Proteins
- Leucine-Rich Repeat Proteins
- Membrane Proteins
- Plant Proteins
- Proteins
- RNA, Messenger
- Flagellin
- Protein Kinases
- FLS2 protein, Arabidopsis