Ribozyme diagnostics comes of age

Chem Biol. 2004 Jul;11(7):894-5. doi: 10.1016/j.chembiol.2004.07.002.

Abstract

Biosensing ribozymes could soon be used to diagnose viral infection. The Kossen group from Sirna Therapeutics have developed a sensitive, high-throughput means of screening for hepatitis C virus, using their target activated half-ribozyme technology, as reported in the June issue of Chemistry & Biology.

Publication types

  • Comment

MeSH terms

  • Biosensing Techniques*
  • Hepacivirus / isolation & purification*
  • Hepatitis C / diagnosis*
  • Humans
  • RNA, Catalytic*

Substances

  • RNA, Catalytic