Concerns regarding nano-sized titanium dioxide dermal penetration and toxicity study

Toxicol Lett. 2010 Feb 1;192(2):268-9. doi: 10.1016/j.toxlet.2009.10.007. Epub 2009 Oct 28.

Abstract

Drawing accurate conclusions from toxicology studies is of critical importance, including the relatively new field of nanotoxicology, as results of these toxicity studies will likely have significant impact on regulatory decisions with regard to their use in consumer products, as well as consumer understanding of these materials. Therefore, we feel it necessary to point out our concerns with the recent report by Wu and colleagues (Wu et al., 2009).

Publication types

  • Comment
  • Letter

MeSH terms

  • Administration, Cutaneous
  • Animals
  • Housing, Animal
  • Hydroxyproline / metabolism
  • Metal Nanoparticles / administration & dosage
  • Metal Nanoparticles / toxicity*
  • Mice
  • Models, Animal
  • Swine
  • Titanium / toxicity*
  • Toxicity Tests / methods

Substances

  • titanium dioxide
  • Titanium
  • Hydroxyproline