Personal reflections on the origins and emergence of recombinant DNA technology

Genetics. 2010 Jan;184(1):9-17. doi: 10.1534/genetics.109.112144.

Abstract

The emergence of recombinant DNA technology occurred via the appropriation of known tools and procedures in novel ways that had broad applications for analyzing and modifying gene structure and organization of complex genomes. Although revolutionary in their impact, the tools and procedures per se were not revolutionary. Rather, the novel ways in which they were applied was what transformed biology.

Publication types

  • Historical Article

MeSH terms

  • Animals
  • Bacteria / genetics
  • Base Sequence
  • Biotechnology
  • Cloning, Molecular
  • DNA, Recombinant / genetics*
  • Genetic Engineering / history*
  • Genetic Engineering / legislation & jurisprudence
  • Genetic Engineering / methods
  • Government Regulation
  • History, 20th Century
  • Humans

Substances

  • DNA, Recombinant