Abstract
In Saudi Arabia, including regions of Riyadh and Al Ahsa, pseudoparticle neutralisation (ppNT) and microneutralisation (MNT) tests detected no antibodies to Middle East Respiratory Syndrome coronavirus (MERS-CoV) in sheep (n= 100), goats (n= 45), cattle (n= 50) and chickens (n= 240). Dromedary camels however, had a high prevalence of MERS-CoV antibodies. Bovine coronavirus (BCoV) infected sera from cattle had no cross-reactivity in MERS-CoV ppNT or MNT, while many dromedary camels’ sera reacted to both BCoV and MERS-CoV. Some nevertheless displayed specific serologic reaction profiles to MERS-CoV.
Publication types
- Research Support, N.I.H., Extramural
- Research Support, Non-U.S. Gov't
MeSH terms
- Animals
- Antibodies, Neutralizing / blood*
- Antibodies, Viral / blood*
- Camelus / blood
- Case-Control Studies
- Coronavirus / immunology*
- Coronavirus / isolation & purification
- Coronavirus Infections / blood
- Coronavirus Infections / epidemiology*
- Coronavirus Infections / virology
- Female
- Humans
- Livestock / blood
- Male
- Middle Aged
- Middle East
- Prevalence
- Respiratory Tract Infections / blood
- Respiratory Tract Infections / epidemiology*
- Respiratory Tract Infections / virology
- Saudi Arabia / epidemiology
- Seroepidemiologic Studies
- Syndrome
Substances
- Antibodies, Neutralizing
- Antibodies, Viral