The role of superspreading in Middle East respiratory syndrome coronavirus (MERS-CoV) transmission

Euro Surveill. 2015 Jun 25;20(25):14-8. doi: 10.2807/1560-7917.es2015.20.25.21167.

Abstract

As at 15 June 2015, a large transmission cluster of Middle East respiratory syndrome coronavirus (MERSCoV)was ongoing in South Korea. To examine the potential for such events, we estimated the level of heterogeneity in MERS-CoV transmission by analyzing data on cluster size distributions. We found substantial potential for superspreading; even though it is likely that R0 < 1 overall, our analysis indicates that cluster sizes of over 150 cases are not unexpected forMERS-CoV infection.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Cluster Analysis
  • Coronavirus / isolation & purification
  • Coronavirus / pathogenicity*
  • Coronavirus Infections / epidemiology
  • Coronavirus Infections / transmission*
  • Coronavirus Infections / virology
  • Disease Outbreaks
  • Humans
  • Middle East Respiratory Syndrome Coronavirus / isolation & purification
  • Middle East Respiratory Syndrome Coronavirus / pathogenicity
  • Republic of Korea / epidemiology
  • Severe Acute Respiratory Syndrome / epidemiology
  • Severe Acute Respiratory Syndrome / transmission*
  • Severe Acute Respiratory Syndrome / virology