How Does the Scientific Community Contribute to Gene Ontology?

Methods Mol Biol. 2017:1446:85-93. doi: 10.1007/978-1-4939-3743-1_7.

Abstract

Collaborations between the scientific community and members of the Gene Ontology (GO) Consortium have led to an increase in the number and specificity of GO terms, as well as increasing the number of GO annotations. A variety of approaches have been taken to encourage research scientists to contribute to the GO, but the success of these approaches has been variable. This chapter reviews both the successes and failures of engaging the scientific community in GO development and annotation, as well as, providing motivation and advice to encourage individual researchers to contribute to GO.

Keywords: Annotation; Biocuration; Bioinformatics; Clinical and basic research; Community; Community annotation; Community curation; Curation; Gene Ontology; Genomics; Proteomics; Transcriptomics.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Community Networks
  • Computational Biology / methods
  • Databases, Genetic
  • Gene Ontology*
  • Humans
  • Molecular Sequence Annotation / methods