The Challenges of Vaccine Development against a New Virus during a Pandemic

Cell Host Microbe. 2020 May 13;27(5):699-703. doi: 10.1016/j.chom.2020.04.021.

Abstract

The rapid emergence of a highly pathogenic, readily transmissible coronavirus has resulted in a global pandemic, affecting millions and destabilizing economies. This catastrophe triggered a clarion call for the immediate deployment of a protective vaccine. We describe the unique challenges of developing a vaccine against SARS-CoV-2 in a pandemic setting.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, N.I.H., Intramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Betacoronavirus / immunology*
  • COVID-19
  • Coronavirus Infections / epidemiology
  • Coronavirus Infections / immunology*
  • Coronavirus Infections / prevention & control
  • Humans
  • Pandemics / prevention & control*
  • Pneumonia, Viral / epidemiology
  • Pneumonia, Viral / immunology*
  • Pneumonia, Viral / prevention & control
  • SARS-CoV-2
  • Time Factors
  • Viral Vaccines / immunology*
  • Viral Vaccines / standards
  • Viral Vaccines / supply & distribution

Substances

  • Viral Vaccines