Abstract
A fraction of the covalently closed mitochondrial DNA in mouse L cells contains a replicated heavy-strand segment that is hydrogen bonded to the circular light strand. The inserted single strand is dissociable from the circular duplex at an elevated temperature.
MeSH terms
- Animals
- Carbon Isotopes
- Cell Fractionation
- Centrifugation, Density Gradient
- DNA / analysis*
- DNA / isolation & purification
- Hot Temperature
- L Cells
- Mice
- Microscopy, Electron
- Mitochondria / analysis*
- Molecular Weight
- Nucleic Acid Hybridization
- Protein Conformation*
- Thymidine
Substances
- Carbon Isotopes
- DNA
- Thymidine