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dsDNA viruses genomes range from 4.5 kb to 800 kb
| Family/genus | Type | Min length | Max length | ORF |
| Polyomaviridae | Circular | 4.5 kb | 5 kb | 5-9 |
| Clavaviridae | Circular | 5.3 kb | 5.3 kb | 14 |
| Papillomaviridae | Circular | 6.8 kb | 8.4 kb | 8-10 |
| Corticoviridae | Circular | 10 kb | 10 kb | 21 |
| Plasmaviridae | Circular | 12 kb | 12 kb | 15 |
| Salterprovirus | Linear | 14.5 kb | 14.5 kb | 35 |
| Tectiviridae | Linear | 15 kb | 15 kb | 25-30 |
| Fuselloviridae | Circular | 15 kb | 18 kb | 31-37 |
| Sphaerolipoviridae | Circular | 16 kb | 30 kb | 37 |
| Guttaviridae | Circular | 20 kb | 20 kb | 21 |
| Ampullaviridae | Linear | 24 kb | 24 kb | 56 |
| Globuloviridae | Linear | 28 kb | 28 kb | 45-50 |
| Rudiviridae | Linear | 32 kb | 35 kb | 45-54 |
| Adenoviridae | Linear | 30 kb | 50 kb | 40 |
| Lipothrixviridae | Linear | 13 kb | 56 kb | 39-74 |
| Bicaudaviridae | Circular | 62 kb | 62 kb | 72 |
| Podoviridae | Linear | 16 kb | 70 kb | 20-65 |
| Siphoviridae | Linear | 22 kb | 121 kb | 36-88 |
| Myoviridae | Linear | 100 kb | 170 kb | ~200-300 |
| Baculoviridae | Circular | 80 kb | 180 kb | 100-180 |
| Ascoviridae | Circular | 120 kb | 180 kb | 123-180 |
| Hytrosaviridae | Circular | 120 kb | 190 kb | 108-160 |
| Asfarviridae | Linear | 170 kb | 190 kb | 150 |
| Herpesviridae | Linear | 125 kb | 240 kb | 70-200 |
| Polydnaviridae | Circular (10 or more segments) | 150 kb | 250 kb | 20-30? |
| Nimaviridae | Circular | 300 kb | 300 kb | 184 |
| Iridoviridae | Linear | 102 kb | 303 kb | 102-468 |
| Poxviridae | Linear | 130 kb | 375 kb | 150-300 |
| Phycodnaviridae | Linear | 100 kb | 560 kb | 231-373 |
| Dinodnavirus | Linear | 356 kb | 356 kb | ? |
| Marseillevirus | Circular | 368 kb | 368kb | 457 |
| Pithovirus | Circular | 610 kb | 610 kb | 467 |
| Mimiviridae | Linear | 1200 kb | 1200 kb | 905 |
| Pandoravirus | Linear | 2,473 kb | 2,300 kb | 2556 |