Cambridgeshire's 40-year-old Perry, who has found the best form of his career in recent seasons, compiled breaks of 60, 51 and 66 to beat Thailand's Un-Nooh and claim the £10,000 top prize in China's Jiangsu Province.
It's the second time Perry has won a tournament which counts towards the world ranking list, having won an Asian Tour event in Yixing last season. The world number 13 was also runner-up at this season's Wuxi Classic.
"It's always a surprise to win a tournament because the standard is so high," said Perry. "Some of the Chinese amateurs in this event were as good as professionals.
"We both missed a few balls early in the final, but once I settled down I played well and controlled the match. I felt that if I could cut out the mistakes and keep my safety good then I would get chances.
"I know Thepchaiya is an exceptional talent and I'm sure he'll be in many more finals. Maybe he was a bit nervous today."
Earlier in the semi-finals, Perry came from 3-2 down to edge out Tom Ford 4-3 while Un-Nooh reached his first pro final by beating Mark Williams 4-1.
