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Cellosaurus Hepa-1c1c7 (CVCL_0328)

Cell line name Hepa-1c1c7
Synonyms Hepa 1c1c7; Hepa1c1c7; Hepa 1-clc7
Accession CVCL_0328
Resource Identification Initiative To cite this cell line use: Hepa-1c1c7 (RRID:CVCL_0328)
Comments Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Disease Hepatocellular carcinoma of the mouse (NCIt: C38756)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57L.
Hierarchy Parent: CVCL_S550 (Hepa-1)
Children:
CVCL_3492 (BpRc1) CVCL_9103 (c1 (B6NLxv1c2)) CVCL_9104 (c12 (B15ECiii2))
CVCL_9105 (c35 (B16GBi1c3)) CVCL_9106 (c37 (B7IFi1)) CVCL_9085 (c4 (B13NBii1))
CVCL_EG66 (DR-EcoScreen) CVCL_B3MB (DR-EcoScreen-HS) CVCL_DC19 (H1G1.1c3)
CVCL_DC20 (H1L1.1c2) CVCL_DC21 (H1L1.1c7) CVCL_DC22 (H1L6.1c2)
CVCL_DC23 (H1L6.1c3) CVCL_DC24 (H1L7.5c1) CVCL_DC25 (H1L7.5c3)
CVCL_S549 (HeB5) CVCL_0329 (Hepa-C12) CVCL_0330 (Hepa-C4)
CVCL_AS14 (Hepa1-cl19E4) CVCL_C1LX (Hepa1c1c7 BORIS C68) CVCL_C1LY (Hepa1c1c7 BORIS sf2)
CVCL_DC15 (Hepa1c1c7-M4P2) CVCL_DC14 (Hepa1c1c7-MP)
Sex of cell Female
Category Cancer cell line
STR profile Source(s): PubMed=31220119

Markers:
Mouse STR 1-1 14,15
Mouse STR 1-2 13
Mouse STR 2-1 14
Mouse STR 3-2 10
Mouse STR 4-2 18.3,19.3
Mouse STR 5-5 17,18
Mouse STR 6-4 18,19
Mouse STR 6-7 15
Mouse STR 7-1 25.2
Mouse STR 8-1 15
Mouse STR 11-2 16
Mouse STR 12-1 17,18
Mouse STR 13-1 17.1
Mouse STR 15-3 17,18,19
Mouse STR 17-2 14
Mouse STR 18-3 16,17
Mouse STR 19-2 10,11
Mouse STR X-1 25

Run an STR similarity search on this cell line
Publications

PubMed=4362668; DOI=10.1016/0012-1606(73)90008-0
Bernhard H.P., Darlington G.J., Ruddle F.H.
Expression of liver phenotypes in cultured mouse hepatoma cells: synthesis and secretion of serum albumin.
Dev. Biol. 35:83-96(1973)

PubMed=106390; DOI=10.1073/pnas.76.1.373
Hankinson O.
Single-step selection of clones of a mouse hepatoma line deficient in aryl hydrocarbon hydroxylase.
Proc. Natl. Acad. Sci. U.S.A. 76:373-376(1979)

PubMed=7462248; DOI=10.1016/S0021-9258(19)69799-1
Miller A.G., Whitlock J.P. Jr.
Novel variants in benzo(a)pyrene metabolism. Isolation by fluorescence-activated cell sorting.
J. Biol. Chem. 256:2433-2437(1981)

PubMed=6300048; DOI=10.1016/S0021-9258(18)32693-0
Miller A.G., Israel D., Whitlock J.P. Jr.
Biochemical and genetic analysis of variant mouse hepatoma cells defective in the induction of benzo(a)pyrene-metabolizing enzyme activity.
J. Biol. Chem. 258:3523-3527(1983)

PubMed=18959748; DOI=10.1111/j.1742-4658.2008.06686.x
Choi S.M., Oh H., Park H.
Microarray analyses of hypoxia-regulated genes in an aryl hydrocarbon receptor nuclear translocator (Arnt)-dependent manner.
FEBS J. 275:5618-5634(2008)

PubMed=31220119; DOI=10.1371/journal.pone.0218412
Almeida J.L., Dakic A., Kindig K., Kone M., Letham D.L.D., Langdon S., Peat R., Holding-Pillai J., Hall E.M., Ladd M., Shaffer M.D., Berg H., Li J.-L., Wigger G., Lund S., Steffen C.R., Fransway B.B., Geraghty B., Natoli M., Bauer B.A., Gollin S.M., Lewis D.W., Reid Y.A.
Interlaboratory study to validate a STR profiling method for intraspecies identification of mouse cell lines.
PLoS ONE 14:E0218412-E0218412(2019)

Cross-references
Cell line collections (Providers) ATCC; CRL-2026
BCRC; 60104
BCRJ; 0102
ECACC; 95090613
ICLC; ATL98016
KCLB; 22026
Cell line databases/resources CLO; CLO_0003712
MCCL; MCC:0000224
CLDB; cl1660
CLDB; cl1661
CLDB; cl4932
Lonza; 1224
Anatomy/cell type resources BTO; BTO:0002894
Biological sample resources BioSample; SAMN11397638
Encyclopedic resources Wikidata; Q54882812
Entry history
Entry creation 04-Apr-2012
Last entry update 29-Jun-2023
Version number 17