Cell line name | A-253 | ||||||||||||||||||||
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Synonyms | A 253; A253 | ||||||||||||||||||||
Accession | CVCL_1060 | ||||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: A-253 (RRID:CVCL_1060) | ||||||||||||||||||||
Comments | Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). Part of: COSMIC cell lines project. Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982). Population: Caucasian. Microsatellite instability: Stable (MSS) (Sanger). Omics: Array-based CGH. Omics: CRISPR phenotypic screen. Omics: Deep exome analysis. Omics: Deep quantitative proteome analysis. Omics: DNA methylation analysis. Omics: SNP array analysis. Omics: Transcriptome analysis by microarray. Omics: Transcriptome analysis by RNAseq. Derived from site: In situ; Salivary gland, submandibular gland; UBERON=UBERON_0001736. |
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Sequence variations |
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HLA typing | Source: PubMed=26589293
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Genome ancestry | Source: PubMed=30894373
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Disease | Submandibular gland squamous cell carcinoma (NCIt: C5943) Squamous cell carcinoma of salivary glands (ORDO: Orphanet_500481) |
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Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | ||||||||||||||||||||
Hierarchy | Children:
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Sex of cell | Male | ||||||||||||||||||||
Age at sampling | 54Y | ||||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||||
STR profile | Source(s): ATCC; Cosmic-CLP; IZSLER; PubMed=29923277 Markers:
Run an STR similarity search on this cell line |
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Publications | PubMed=4357758; DOI=10.1093/jnci/51.5.1417 PubMed=327080; DOI=10.1093/jnci/59.1.221 PubMed=833871; DOI=10.1093/jnci/58.2.209 PubMed=6256643; DOI=10.1038/288724a0 PubMed=22282976; DOI=10.1093/carcin/1.1.21 PubMed=3518877; DOI=10.3109/07357908609038260 PubMed=3138611; DOI=10.1177/019459988809800603 DOI=10.1016/B978-0-12-333530-2.50007-1 PubMed=20014447; DOI=10.1002/hed.21311 PubMed=22460905; DOI=10.1038/nature11003 PubMed=26589293; DOI=10.1186/s13073-015-0240-5 PubMed=27397505; DOI=10.1016/j.cell.2016.06.017 PubMed=29923277; DOI=10.1111/odi.12920 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747 PubMed=30971826; DOI=10.1038/s41586-019-1103-9 PubMed=31068700; DOI=10.1038/s41586-019-1186-3 PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010 |
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Cross-references | |||||||||||||||||||||
Cell line collections (Providers) | ATCC; CRL-7902 - Discontinued ATCC; HTB-41 BCRC; 60367 BCRJ; 0322 IZSLER; BS TCL 199 KCLB; 30041 - Discontinued |
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Cell line databases/resources | CLO; CLO_0001569 CLO; CLO_0001570 cancercelllines; CVCL_1060 Cell_Model_Passport; SIDM00796 Cosmic-CLP; 906794 DepMap; ACH-000740 LINCS_LDP; LCL-2034 TOKU-E; 462 |
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Anatomy/cell type resources | BTO; BTO:0003206 | ||||||||||||||||||||
Biological sample resources | BioSample; SAMN03471117 BioSample; SAMN10988034 |
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CRISP screens repositories | BioGRID_ORCS_Cell_line; 824 | ||||||||||||||||||||
Chemistry resources | ChEMBL-Cells; CHEMBL3307893 ChEMBL-Targets; CHEMBL614255 GDSC; 906794 PharmacoDB; A253_39_2019 PubChem_Cell_line; CVCL_1060 |
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Encyclopedic resources | Wikidata; Q54605985 | ||||||||||||||||||||
Gene expression databases | ArrayExpress; E-MTAB-783 ArrayExpress; E-MTAB-2770 ArrayExpress; E-MTAB-3610 GEO; GSM422867 GEO; GSM423670 GEO; GSM886852 GEO; GSM887917 GEO; GSM1669580 |
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Polymorphism and mutation databases | Cosmic; 688036 Cosmic; 906794 Cosmic; 921831 Cosmic; 1017790 Cosmic; 1006471 Cosmic; 1041671 Cosmic; 1995330 Cosmic; 2646649 IARC_TP53; 21160 LiGeA; CCLE_437 Progenetix; CVCL_1060 |
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Proteomic databases | PRIDE; PXD002486 PRIDE; PXD030304 |
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Sequence databases | EGA; EGAS00001000978 | ||||||||||||||||||||
Entry history | |||||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||||
Last entry update | 30-Jan-2024 | ||||||||||||||||||||
Version number | 40 |