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Cellosaurus PNT1A (CVCL_2163)

[Text version]
Cell line name PNT1A
Synonyms PNT1a; PNT-1A; PNT1-a; PNT1/A
Accession CVCL_2163
Resource Identification Initiative To cite this cell line use: PNT1A (RRID:CVCL_2163)
Comments Doubling time: 29.93 +- 1.29 hours (PubMed=21556542).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) [Note=pMK16].
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Prostate, epithelium; UBERON=UBERON_0000428.
Cell type: Epithelial cell of prostate; CL=CL_0002231.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_4804 (PNT1)
Children:
CVCL_JX33 (PNT1A serum free)
Sex of cell Male
Age at sampling 35Y
Category Transformed cell line
STR profile Source(s): PubMed=11416159

Markers:
Amelogenin X,Y
D8S1179 10,12
D18S51 16
D21S11 27,28
FGA 24
TH01 6
vWA 17,19

Run an STR similarity search on this cell line
Publications

PubMed=7558421; DOI=10.1002/ijc.2910620613
Degeorges A., Hoffschir F., Cussenot O., Gauville C., Le Duc A., Dutrillaux B., Calvo F.
Recurrent cytogenetic alterations of prostate carcinoma and amplification of c-myc or epidermal growth factor receptor in subclones of immortalized PNT1 human prostate epithelial cell line.
Int. J. Cancer 62:724-731(1995)

PubMed=21556542; DOI=10.3892/ijo.6.2.333
Berthon P., Cussenot O., Hopwood L., Le Duc A., Maitland N.J.
Functional expression of SV40 in normal human prostatic epithelial and fibroblastic cells: differentiation pattern of nontumorigenic cell-lines.
Int. J. Oncol. 6:333-343(1995)

PubMed=11416159; DOI=10.1073/pnas.121616198
Masters J.R.W., Thomson J.A., Daly-Burns B., Reid Y.A., Dirks W.G., Packer P., Toji L.H., Ohno T., Tanabe H., Arlett C.F., Kelland L.R., Harrison M., Virmani A.K., Ward T.H., Ayres K.L., Debenham P.G.
Short tandem repeat profiling provides an international reference standard for human cell lines.
Proc. Natl. Acad. Sci. U.S.A. 98:8012-8017(2001)

PubMed=11694337; DOI=10.1016/S0303-7207(01)00669-4
Avances C., Georget V., Terouanne B., Orio F. Jr., Cussenot O., Mottet N., Costa P., Sultan C.
Human prostatic cell line PNT1A, a useful tool for studying androgen receptor transcriptional activity and its differential subnuclear localization in the presence of androgens and antiandrogens.
Mol. Cell. Endocrinol. 184:13-24(2001)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

Cross-references
Cell line collections (Providers) ECACC; 95012614
Cell line databases/resources CLO; CLO_0008475
CLDB; cl3926
Anatomy/cell type resources BTO; BTO:0003068
Chemistry resources ChEMBL-Cells; CHEMBL4513117
ChEMBL-Targets; CHEMBL4513131
PubChem_Cell_line; CVCL_2163
Encyclopedic resources Wikidata; Q54947679
Gene expression databases GEO; GSM827411
GEO; GSM1374835
Entry history
Entry creation 04-Apr-2012
Last entry update 05-Oct-2023
Version number 23