Evolutionary genetics
Authored by an internationally prominent figure in the field, Evolutionary Genetics unites the molecular and population approaches to evolution to show how population genetics can be applied to real biological problems. It explores the mechanisms of evolution, covering basic population and quantitative genetics; evolutionary game theory; evolution of behavior; prokaryote evolution; evolution of genomes; sex, recombination, breeding systems, and sexual selection; speciation; and macroevolution. Throughout, science is viewed as a dynamic activity rather than a body of received doctrine, and current research is given a comprehensive treatment. End-of-chapter problems, with answers and explanations at the back of the book, along with computer projects, allow students to practice the skills central to problem-solving and model-making in population and evolution
xii, 325 pages : illustrations ; 25 cm
9780198542155, 0198542151
18069049
Part 1 Evolution by natural selection: Darwin's theory; evolution "in vitro"; Lamark, Weismann and the central dogma. Part 2 Models of populations: models of population growth; selection in an asexual population; the accuracy of replication; genetic drift in finite populations. Part 3 Evolution in diploid populations: gene frequencies and the Hardy-Weinberg ratio; the concept of fitness; the spread of a favourable gene. Part 4 The variability of natural populations: the evidence for genetic variability; mutation; the maintenance of variation. Part 5 Evolution at more than one locus: linkage disequilibrium; heterostyly in plants; mimicry in butterflies; linkage disequilibrium in natural populations; normalizing selection and linkage disequilibriums. Part 6 Quantitative genetics: nature and nurture; the additive genetic model; a more realistic model; experiments in artificial selection; quantitative variation and fitness; the maintenance of genetic variance for quantitative traits. Part 7 A model of phenotypic evolution: pairwise interactions; some extensions of the model; will a sexual population evolve to an ESS? Part 8 Finite and structured populations: inbreeding; genetic drift; the rate of neutral molecular evolution; mitochondrial DNA; migration and differentiation between populations; the establishment of a new favourable mutation. Part 9 Evolution in structured populations: selection in trait groups; the evolution of co-operation - synergistic selection, relatedness; the group as the unit of evolution; the shifting balance theory. Part 10 The evolution of prokaryotes: the evolution of gene function; phages, plasmids and transposable elements; the evolution of phages and their hosts, plasmids, transposons; the population genetics of "E. coli"; the evolution of viruses. Part 11 The evolution of the eukaryotic genome: the nature of the genome; the haemoglobin gene family; duplication and the increase of DNA content; the ribosomal gene; unequal crossing over and gene conversion; repetitive DNA; karyotypic evolution. Part 12 The evolution of genetic systems - sex and recombination: the natural history of eukaryotic sex; the evolutionary significance of sex; the evolution of recombination. Part 13 The evolution of genetic systems - some consequences of sex: the sex ratio; selfing and outcrossing; hermaphroditism; sexual selection. Part 14 Macroevolution: species and speciation; patterns of evolution; coevolution.