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Evolving Concepts for Use of Stem Cells and Tissue Engineering for Cardiac Regeneration

Evolving Concepts for Use of Stem Cells and Tissue Engineering for Cardiac Regeneration

Jahnavi Sarvepalli, Rajalakshmi Santhakumar, Rama Shanker Verma
Copyright: © 2019 |Pages: 35
ISBN13: 9781522581857|ISBN10: 1522581855|EISBN13: 9781522581864
DOI: 10.4018/978-1-5225-8185-7.ch024
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MLA

Sarvepalli, Jahnavi, et al. "Evolving Concepts for Use of Stem Cells and Tissue Engineering for Cardiac Regeneration." Coronary and Cardiothoracic Critical Care: Breakthroughs in Research and Practice, edited by Information Resources Management Association, IGI Global, 2019, pp. 509-543. https://doi.org/10.4018/978-1-5225-8185-7.ch024

APA

Sarvepalli, J., Santhakumar, R., & Verma, R. S. (2019). Evolving Concepts for Use of Stem Cells and Tissue Engineering for Cardiac Regeneration. In I. Management Association (Ed.), Coronary and Cardiothoracic Critical Care: Breakthroughs in Research and Practice (pp. 509-543). IGI Global. https://doi.org/10.4018/978-1-5225-8185-7.ch024

Chicago

Sarvepalli, Jahnavi, Rajalakshmi Santhakumar, and Rama Shanker Verma. "Evolving Concepts for Use of Stem Cells and Tissue Engineering for Cardiac Regeneration." In Coronary and Cardiothoracic Critical Care: Breakthroughs in Research and Practice, edited by Information Resources Management Association, 509-543. Hershey, PA: IGI Global, 2019. https://doi.org/10.4018/978-1-5225-8185-7.ch024

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Abstract

The incidence of cardiovascular disease (CVD) in adults are increasing worldwide with impaired repair mechanisms, leading to tissue and organ failure. With the current advancements, life expectancy has improved and has led to search for new treatment strategies that improves tissue regeneration. Recently, stem cell therapy and tissue engineering has captured the attention of clinicians, scientists, and patients as alternative treatment options. The overall clinical experience of these suggests that they can be safely used in the right clinical setting. Ultimately, large outcome trials will have to be conducted to assess their efficacy. Clinical trials have to be carefully designed and patient safety must remain the key concern. At the same time, continued basic research is required to understand the underlying mechanism of cell-based therapies and cell tissue interactions. This chapter reviews the evolving paradigm of stem cell therapy and tissue engineering approaches for clinical application and explores its implications.

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